Anti-Mouse Interferon Gamma Antibody (Clone H22) – Purified in vivo GOLD™ Functional Grade - 1.0 mg I-438-1.0 mg from Leinco Technologies, Inc.

Product Specs
ItemAnti-Mouse Interferon Gamma Antibody (Clone H22) – Purified in vivo GOLD™ Functional Grade - 1.0 mg
CompanyLeinco Technologies, Inc.
Price Pricing Info Supplier Page View Company Product Page
Catalog NumberI-438-1.0 mg
Quantity1.0 mg
Applicationsin vivo, IP, N, WB
Concentration≥ 5.0 mg/ml
Conjugate/TagUnconjugated
FormatThis monoclonal antibody is aseptically packaged and formulated in 0.01 M phosphate buffered saline (150 mM NaCl) PBS pH 7.2 - 7.4 with no carrier protein, potassium, calcium or preservatives added. Due to inherent biochemical properties of antibodies, certain products may be prone to precipitation over time. Precipitation may be removed by aseptic centrifugation and/or filtration
Purity≥95% monomer by analytical SEC, >95% by SDS Page
ReactivityMouse
TargetInterferon Gamma
IsotypeIgG
CloneH22
HostArmenian Hamster
ImmunogenPurified Recombinant Mouse IFN-γ (>98%)
NCBI Full Gene Nameinterferon gamma
NCBI Gene AliasesIFN-g, If2f, Ifg
ClonalityMonoclonal Antibody
Research AreaImmunology

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Leinco Technologies, Inc.

410 Axminister Drive

St. Louis, Missouri 63026

United States

Phone: (636) 230-9477
Orders or Customer Support: (800) 538-1145
Technical Support: (800) 538-1145

Email: leincoglobal@leinco.com

Company Profile

Website: www.leinco.com

(1) The IFN-Î³ receptor promotes immune dysregulation and disease in STING gain-of-function miceJCI InsightSeptember 8, 2022W. Alexander Stinson, Cathrine A. Miner, Fang R. Zhao, Annena Jane Lundgren, Subhajit Poddar, Jonathan J. Minerthe neutralizing capacity of the anti–IFN-γ antibody, 20 μg/mL anti-mouse IFN-γ antibodies (Leinco, I-438) or isotype control antibody (Leinco, I-140) were incubated with recombinant murine IFN-γ (10 ng/mL)

(2) Commensal Cryptosporidium colonization elicits a cDC1-dependent Th1 response that promotes intestinal homeostasis and restricts other infectionsImmunityNovember 1, 2021Emilie V. Russler-Germain, Jisun Jung, Aidan T. Miller, Shannon Young, Jaeu Yi, Alec Wehmeier, Lindsey E. Fox, Kristen J. Monte, Jiani N. Chai, Devesha H. Kulkarni, et al.and 0.5 mg/ml vancomycin in drinking water and 250 μg anti-IFNγ blocking antibody clone H22 (Leinco #I-438) for 2 days before infection. Feces were resuspended in cold sterile PBS by vortexing. Large debris

(3) The Intestinal Microbiome Restricts Alphavirus Infection and Dissemination through a Bile Acid-Type I IFN Signaling AxisCellAugust 20, 2020Winkler ES, Shrihari S, Hykes BL Jr, Handley SA, Andhey PS, Huang YS, Swain A, Droit L, Chebrolu KK, Mack M, et al.Ifnar1−/− mice were treated with an anti-IFN-γ blocking monoclonal antibody (200 ug, MAb H22; Leinco, I-438) or an IgG isotype control antibody (200 ug MAb PIP; Leinco, I-140) 1 day prior to infection with CHIKV

(4) Interferon Regulatory Factor 1 Protects against Chikungunya Virus-Induced Immunopathology by Restricting Infection in Muscle CellsJournal of virologyNovember 15, 2017Nair S, Poddar S, Shimak RM, Diamond MS.1 day postinfection were administered an anti-IFN-␥ blocking monoclonal antibody (MAb H22; Leinco, I-438) or an IgG isotype control antibody (MAb PIP; Leinco, I-140). Foot swelling and virological titers were

(5) Temporally Distinct PD-L1 Expression by Tumor and Host Cells Contributes to Immune EscapeCancer immunology researchFebruary 1, 2017Noguchi T, Ward JP, Gubin MM, Arthur CD, Lee SH, Hundal J, Selby MJ, Graziano RF, Mardis ER, Korman AJ, et al.

(6) Selective Blockade of Interferon-α and -β Reveals Their Non-Redundant Functions in a Mouse Model of West Nile Virus InfectionPloS oneJanuary 1, 2015Sheehan KC, Lazear HM, Diamond MS, Schreiber RD.

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Anti-Mouse Interferon Gamma Antibody (Clone H22) – Purified in vivo GOLD™ Functional Grade - 1.0 mg from Leinco Technologies, Inc.

Leinco Technologies, Inc.

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Anti-Mouse Interferon Gamma Antibody (Clone H22) – Purified in vivo GOLD™ Functional Grade - 1.0 mg from Leinco Technologies, Inc.

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